Research and Development

Over the past decade, the Institute’s research has focussed on the rapidly developing area of regenerative medicine, specifically the development of natural tissue scaffolds to replace surgically removed or traumatised tissues.

The objective of the tissue engineering and regenerative medicine group is to deliver, in collaboration with leading clinicians, therapies for targeted clinical disorders/diseases.

We use innovative ways of combining both biological and hybrid scaffolds with different cell populations to create functional tissue (sheets and organs) suitable for clinical use.

Areas under investigation include the respiratory system (trachea), bowel and liver and wound healing constructs (skin and fistulas). Our strength is in our ability to develop new technologies for producing scaffolds and adjuncts (e.g. stents), together with novel ways of co culturing and manipulating mesenchymal stem cells and the use of wide ranging imaging systems for in vivo testing in different pre-clinical models.

Some of our most notable Achievements

GLP/GMP decellularised/recellularised Trachea implanted into human clinical case.

Decellularised/recellularised Larynx with pre-clinical phase complete. (Clinical phase – Jan 2014)

Fusion of Laparoscopy & Endoscopy for novel resection procedure for polyps & T1/T2 bowel cancer.

Pressure activated stoma continence control device – Tested and delivered.


Innovative Procedures
  • Regenerative Medicine
  • Tissue Specific Decell
  • Biological/Synthetic Scaffolds
  • Perfusion Recell
  • Stem Cell Therapy
  • Device Design & Refinement
  • Novel Surgical Techniques
  • Orthopaedic Implants
  • Preclinical Models


Training To Suit
  • Microvascular Surgery
  • Advanced Microsurgery
  • Laparoscopy
  • Endoscopy & Gastroscopy
  • Basic Gastrointestinal Techniques
  • Basic/Advanced Surgical Skills
  • Undergraduate
  • Postgraduate
  • Endovascular Skills

Find out more about NPIMR


About Us

Further information regarding our variety of services can be found here on our website, alternatively, please feel free to contact us using the form below, or by calling our office on 020 8869 3265.

Contact NPIMR


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